Reflect, please on the history of marketing and selling the “harmless” active ingredient in the weed-killer Round-up®. The company which Monsanto bought, had discovered this master-chelator could dissolve most metal scale deposits in boilers and pipes. Glyphosate levels in our food chain took a monster leap upward in 1980-85, when (it being deemed so harmless) glyphosate spray was recommended to kill wheat and other grain crops, just prior to harvest. Thus the “weedicide” became instead a “cropicide” (11). Sprayed on your food at harvest-time, the chemical moves directly into the grain to where seed embryos are being pre-formed and joins the seed part which becomes flour and that we eat. So, if you ever doubted hundreds of privately paid-for tests show now that WE EAT IT! (12) (13).
Glyphosate is the most used pesticide in the history of the world. Agribusinesses and farmers sprayed 300 million pounds of RoundUp in 2016 alone. Over 8.6 billion pounds worldwide since it was introduced in 1974––nearly 75% of that in just the last 10 years.
The bioaccumulation in our food supply, in our soil, in our water, is pervasive
Critical information about health is found in this brief but important summary of recent work in progress by Anthony Samsel and Stephanie Seneff. This news, both published and unpublished, is dire.
How the World’s Most Powerful Weed Killer Works
Glyphosate’s weed-killing action is entirely due to the disruption of a single enzyme.
All the millions and millions of gallons of RoundUp flooding the world every single year are all to stop one enzyme: 5-enolpyruvylshikimate 3-phosphate synthase, or EPSP-Synthase.
This enzyme is essential to a plant’s survival.
It is the critical link in a biochemical process that creates the “aromatic amino acids” (amino acids with a ring attached): phenylalanine, tryptophan, and tyrosine. 
Every plant dies without the ability to make these 3 critical amino acids.
How Monsanto Can Claim RoundUp is “Safe”
What’s interesting about these 3 amino acids, is that humans can’t make them. We call them “essential amino acids,” meaning we have to get them from our diet––mostly from plants.
Therefore Monsanto claims that because humans don’t have this particular enzyme, glyphosate is safe for use.
But there is one glaring problem here:
Humans are made of amino acids. The same glycine-glyphosate substitution happens in our bodies.
But before we get into details of how this is a problem, let’s look a little deeper at how glyphosate works.
Why does glyphosate affect the EPSP-S enzyme?
Enzymes work by creating an “active site” that catalyzes a chemical reaction
For EPSP-Synthase the active site is a small “pocket” created by glycine. Glycine’s small size makes the space for the biochemical magic to happen.
However, if a cell accidentally uses a glyphosate molecule instead of glycine, that extra “phosate” group fills up the pocket and blocks the active site.
Without an active site, the reaction cannot happen. It’s like someone changing the lock on your door; the key just won’t fit.
When this happens to the EPSP-Synthase enzyme, the plant (or bacteria or fungi) cannot make the amino acids it needs to function and the organism dies .
This raises a new question: if cells really use glyphosate like glycine, wouldn't we see it in other places also?
Wouldn’t it cause more problems in other areas associated with glycine?
The answer points to some of the most mysterious and tragic epidemics of our time.
It is not hyperbole to say "glyphosate substitution" (the loss of three Amino Acids) may well be considered to be the cause of most of the idiopathic (unsolved) chronic diseases now rising in human world populations as glyphosate may continue to increase in our diets. The extensive immune damage from a single glyphosate gut disruption, likely leaves life-long auto-immune predilection. - Avoiding Glyphosate
Glyphosate, Collagen and Chronic Pain
Collagen contains the highest concentration of glycine of any protein: nearly 35% glycine by weight.
And what do we see with glyphosate?
Again, Monsanto’s internal studies reveal glyphosate accumulates the most in connective tissue and bones .
Collagen is the single most abundant protein in our body. It makes the fascia between your internal organs, makes your skin supple, protects your joints, and forms your ligaments.
Its structure forms a tight, springy helix, which holds water as a cushion.
When glyphosate is substituted for glycine, the structure loses its shape. The elasticity and strength become compromised. The joints lose their cushion.
This is very likely to create chronic joint pain––one of the core drivers of the opioid epidemic in the U.S. 
Collagen is also a critical player in gut issues, including inflammatory bowel disease and irritable bowel syndrome. If collagen is malformed, gut function is also likely to be disrupted .
The Tip of the Iceberg
There is a correlation between Glyphopho-Food and Food Allergies, Gut Peristalsis and Myosin Sabotage and The Autism Connection and Impaired Detox and Digestion. In fact there are 20 diseases in the USA that correlate with the rise of Glyphosate and GMOs in our food supply.
This is only the beginning. If we look for other potential health issues with glycine-dependent proteins, glyphosate may be implicated in the massive increase in Parkinson’s disease, Alzheimer’s disease, autoimmune conditions, infertility, and cancer.
What happens if one in a thousand proteins are mis-manufactured by a compound which does not break down as was supposed? Why care about deficient F, Y and W? Well, to put it bluntly, Y is precursor to dopamine (that when fails, produces Parkinson’s disease). W is precursor to both melatonin (without which no brain repair during sleep) and serotonin, also essential for brain well-being and for gut food passage. Without both serotonin and dopamine, any person would likely be sleepless, and possibly exhibit severe mental derangement. Lacking self-esteem, some might become suicidal, or enraged and potentially commit mass mayhem – possibly indiscriminate murders about which their family and friends would then remain in disbelief, clueless about real causes. Could this clearly be a case of de facto government sanctioned poisoning?
Please read the article in full: https://martincmichener.wordpress.com/avoiding-glyphosate/
Read more about the impact of amino acid replacement and its effect on our body at https://www.bodyhealth.com/blogs/news/glyphosate-in-your-body
- Ridley, W.P. & Mirly, K. The metabolism of glyphosate in Sprague Dawley rats. Part I. Excretion and tissue distribution of glyphosate and its metabolites following intravenous and oral administration (unpublished study MSL-7215 conducted by Monsanto’s Environmental Health Laboratory and submitted to the EPA July 1988)(MRID#407671-01) (1988)
- Protective effects of lignite extract supplement on intestinal barrier function in glyphosate-mediated tight junction injury, JJ Gildea, DA Roberts, Z Bush - J Cin Nutr Diet, 2017
14. Crop Dessication. s.l. : Everipedia https://everipedia.org/wiki/Crop_desiccation/.
15. Moms Across America: . Honeycutt, Zen. s.l. : https://www.momsacrossamerica.com/state_bans.
16. Glyphosate Is Destructor of Human Health and Biodiversity. Mason, R. s.l. : Sustainable Pulse, 2013.
Did Monsanto know the impact on human health? Clearly the answer is YES. They knew their billion dollar product could harm and kill humans. The initial reports of licensing appear now all to have been written by Monsanto employees and consultants, without attribution of interest conflicts. Some relevant postings of decisions have been removed.